چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Metformin is an oral anti-hyperglycemic derivative extensively used for the treatment of type II diabetes. Following oral administration, metformin exhibits an incomplete absorption and therefore repeated administrations of high doses of this drug are required for successful therapy due to its short biological half-life. For this, development of novel drug delivery systems for metformin might be useful to decrease the dosing frequency, to enhance its bioavailability, to reduce gastrointestinal adverse effects, and to be helpful for effective use of metformin in diabetes treatment. In this review, we present microparticulate gastroretentive delivery systems developed to enhance the oral bioavailability of metformin. |
| نویسنده | نفر چندم مقاله |
|---|---|
| سارا سلاطین | اول |
| میترا جلوه گری | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| AJBSR.MS.ID.001195(2).pdf | 1399/03/15 | 273789 | دانلود |
