Targeting immune checkpoints: Building better therapeutic puzzle in pancreatic cancer combination therapy
Targeting immune checkpoints: Building better therapeutic puzzle in pancreatic cancer combination therapy
نویسندگان: سعیده راضی صوفیانی , الهام گلی , حسین عبدالهی , بهزاد برادران , سینا عبدکریمی
کلمات کلیدی: chemotherapy, combination therapy, CTLA-4, immune checkpoint, pancreatic cancer, PD-1
نشریه: 10920 , 2 , 3 , 2020
| نویسنده ثبت کننده مقاله |
بهزاد برادران |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات ایمونولوژی |
| کد مقاله |
72388 |
| عنوان فارسی مقاله |
Targeting immune checkpoints: Building better therapeutic puzzle in pancreatic cancer combination therapy |
| عنوان لاتین مقاله |
Targeting immune checkpoints: Building better therapeutic puzzle in pancreatic cancer combination therapy |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Pancreatic cancer is related to a very weak diagnosis; the close parallel between disease incidence and mortality rates from pancreatic cancer reflects the fatal nature of
this disease. Although early detection procedures are growing, they are not applicable yet for pancreatic cancer. The majority of cancer patients suffer from advanced
disease, in which surgery has no potential effect. Based on the growing evidence, it
is predicated that cancer immunotherapy alone or in combination will probably be an
essential section of different cancer treatment methods. There are different kinds of
immune processes, including various antitumour and tumour-promoting leukocytes.
Moreover, tumour cells utilise numerous approaches to overwhelm the immune response. Use of antibody in the therapeutic protocols is proving significant success
and is probably a key element of cancer treatment. This method is directed against
numerous negative immunologic regulators and immune checkpoints. In the present
review, the clinical outlines of immune checkpoint inhibition are discussed in pancreatic cancer |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 416-Targeting immune checkpoints Building better therapeutic.pdf | 1399/05/07 | 688103 | دانلود |