The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects
The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects
نویسندگان: ناصر آقا محمد زاده , ندا دولت خواه , سید کاظم شکوری بیلانکوهی , سعید حسن پور
کلمات کلیدی: 25-hydroxy vitamin D, diabetes mellitus, Blood pressure, quality of life
نشریه: 6255 , 3 , 11 , 2020
| نویسنده ثبت کننده مقاله |
ندا دولت خواه |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
طب فیزیکی وتوانبخشی |
| کد مقاله |
72384 |
| عنوان فارسی مقاله |
The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects |
| عنوان لاتین مقاله |
The relationship between serum 25-hydroxy vitamin D and blood pressure and quality of life in overweight and obese patients with type 2 diabetes mellitus compared with healthy subjects |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Background: Vitamin D is one of the known lipoprotein hormones with metabolic properties. We aimed to determine the serum 25-hydroxy vitamin D concentration in overweight/obese subjects with diabetes mellitus type Ⅱ (DM Ⅱ) in association with systolic and diastolic blood pressure and quality of life compared with healthy participants.
Methods: The current case-control study was carried out among 80 overweight/obese subjects with DM Ⅱ, and 77 healthy subjects matched by sex, age and body mass index (BMI). Serum 25-hydroxyvitamin D concentration was measured by ELISA method. In order to examine the quality of life, the Persian version of SF36 questionnaire was used.
Results: There was significant difference between diabetic and healthy subjects considering serum 25-hydroxyvitamin D concentration (p-value = 0.012). Serum 25-hydroxyvitamin D concentration was inversely correlated with diastolic blood pressure (p-value = 0.02) and positively associated with physical function (p-value <0.001), social function (p-value <0.001) and general health (p-value <0.001) components of quality of life in diabetic subjects and physical health sub-scale (p-value = 0.004) in all participants.
Conclusion: Serum 25-hydroxyvitamin D concentration was significantly lower in diabetic subjects in comparison with healthy controls. There was a significant reverse relationship between serum concentrations of 25-hydroxyvitamin D with diastolic blood pressure and on the other hand, a significant positive relationship with physical function, social function and general health components and physical health subscale of quality of life in participants with DM Ⅱ. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| (5) dr dolatkhah-1385-2 (1).pdf | 1399/04/08 | 625793 | دانلود |