چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Evidence shows that fluconazole prophylaxis is an effective treatment against invasive fungal infections in preterm neonates, however, the most efficient schedule of fluconazole prophylaxis for the colonization and mortality of invasive candidiasis (IC) is unknown. This systematic review and meta-analysis aimed to assess the efficiency of different prophylactic fluconazole schedules in controlling IC colonization, infection, and mortality in very low birth weight (VLBW) and extremely low birth weight (ELBW) infants in neonatal intensive care units. We searched the PubMed, Scopus, Embase, and Cochrane databases using the keywords “candida,” “invasive candidiasis,” “IC,” “fluconazole prophylaxis,” “preterm infants,” “very low birth weight infants,” “VLBW,” “extremely low birth weight,” and “ELBW.” Mortality was significantly decreased in a meta-analysis of studies using different fluconazole prophylaxis regimens. The meta-analysis also indicated a significant decrease in the incidence of IC-associated mortality in ELBW infants using the same fluconazole prophylaxis schedules. Future studies should explore the effectiveness of other different fluconazole prophylaxis schedules on IC colonization, infection, and mortality. |
| نویسنده | نفر چندم مقاله |
|---|---|
| محمود رباطی انارکی | اول |
| شهرام عبدلی اسکویی | سوم |
| مسعود نوری وسکه | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| cep-2019-01431.pdf | 1399/12/16 | 1643116 | دانلود |
