چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| There is ongoing debate on how B cells contribute to the pathogenesis of multiple sclerosis (MS). The success of B-cell targeting therapies in MS highlighted the role of B cells, particularly the antibody-independent functions of these cells such as antigen presentation to T cells and modulation of the function of T cells and myeloid cells by secreting pathogenic and/ or protective cytokines in the central nervous system. Here, we discuss the role of different antibody-dependent and antibody-independent functions of B cells in MS disease activity and progression proposing new therapeutic strategies for the optimization of B-cell targeting treatments. |
| نویسنده | نفر چندم مقاله |
|---|---|
| توحید غریبی | اول |
| زهره بابالو | دوم |
| آرزو حسینی | سوم |
| فاروق معروفی | چهارم |
| عباس ابراهیمی کلان | پنجم |
| بهزاد برادران | هفتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| The role of B cells in the immunopathogenesis of multiple sclerosis.pdf | 1399/05/08 | 709858 | دانلود |
