| Background: Catastrophic health expenditures (CHE) are of concern to policy makers and can prevent individuals
accessing efective health care services. The exposure of households to CHE is one of the indices used to evaluate
and address the level of fnancial risk protection in health systems, which is a key priority in the global health policy
agenda and an indicator of progress toward the UN Sustainable Development Goal for Universal Health Coverage.
This study aims to assess the CHE at population and disease levels and its infuencing factors in Iran.
Methods: This study is a systematic review and meta-analysis. The following keywords and their Persian equivalents
were used for the review: Catastrophic Health Expenditures; Health Equity; Health System Equity; Financial Contribu‑
tion; Health Expenditures; Financial Protection; Financial Catastrophe; and Health Financing Equity. These keywords
were searched with no time limit until October 2019 in PubMed, Web of Science, Scopus, ProQuest, ScienceDirect,
Embase, and the national databases of Iran. Studies that met a set of inclusion criteria formed part of the meta-analy‑
sis and results were analyzed using a random-efects model.
Results: The review identifed 53 relevant studies, of which 40 are conducted at the population level and 13 are
disease specifc. At the population level, the rate of CHE is 4.7% (95% CI 4.1% to 5.3%, n=52). Across diseases, the
percentage of CHE is 25.3% (95% CI 11.7% to 46.5%, n=13), among cancer patients, while people undergoing dialysis
face the highest percentage of CHE (54.5%). The most important factors infuencing the rate of CHE in these studies
are health insurance status, having a household member aged 60–65 years or older, gender of the head of household,
and the use of inpatient and outpatient services.
Conclusion: The results suggest that catastrophic health spending in Iran has increased from 2001 to 2015 and has
reached its highest levels in the last 5 years. It is therefore imperative to review and develop fair health fnancing
policies to protect people against fnancial hardship. This review and meta-analysis provides evidence to help inform
efective health fnancing strategies and policies to prioritise high-burden disease groups and address the determi‑
nants of CHE. |