Epidemiological and Clinical Characteristics of inflammatory Bowel Disease in Patients from Northwestern Iran.

Epidemiological and Clinical Characteristics of inflammatory Bowel Disease in Patients from Northwestern Iran.


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نویسندگان: کوروش مسندی شیرازی , محمد حسین صومی , یوسف بافنده , پریسا رضائی فر , سید کاظم میری نژاد

کلمات کلیدی: Inflammatory bowel disease; Iran; Demographic; Disease severity

نشریه: 24127 , 2 , 5 , 2013

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نویسنده ثبت کننده مقاله سید کاظم میری نژاد
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه بیماری های گوارش و کبد
کد مقاله 72208
عنوان فارسی مقاله Epidemiological and Clinical Characteristics of inflammatory Bowel Disease in Patients from Northwestern Iran.
عنوان لاتین مقاله Epidemiological and Clinical Characteristics of inflammatory Bowel Disease in Patients from Northwestern Iran.
ناشر 8
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت

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BACKGROUND There are few reports from Iran about the epidemiology and clinical features of inflammatory bowel disease (IBD). This study aims to determine the epidemiologic profle and clinical features of IBD in Northwest Iran referral centers. METHODS In a cross-sectional setting, we evaluated 200 patients with defnitive diagnoses of IBD who referred to Tabriz educational hospitals during the period of 2005 to 2007. Demographic characteristics as well as patients’ clinical profles were evaluated. Disease activity and severity were determined by the Crohn’s Disease Activity Index and Truelove and Witt’s classifcation of ulcerative colitis (UC). The related probable demographic factors were tested. RESULTS Of the 200 IBD patients, 183 (91.5%) were diagnosed with UC and 17 (8.5%) with Crohn’s disease (CD). There was a positive frst degree relative of IBD in 10.9% of UC and 11.8% of CD patients. Abdominal pain was the primary presenting symptom in 25.7% of UC patients and in 58.8% of those with CD. Among UC patients, left-sided colitis was the main feature (52.5%); while in patients with CD, colon involvement was predominant (52.9%). There was no signifcant contributor for activity or severity of disease noted among demographic factors. CONCLUSION The occurrence of UC was much higher than CD. The onset of IBD occurred in younger ages with a predominance in males. Left-sided colitis in UC and colon involvement in CD was common. Mostly, the pattern of IBD was mild to moderate with good response to pharmacotherapy. Disease activity and severity were unaffected by demographic features.

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نویسنده نفر چندم مقاله
کوروش مسندی شیرازیاول
محمد حسین صومیدوم
یوسف بافندهسوم
پریسا رضائی فرششم
سید کاظم میری نژادهشتم

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