Effect of Calcitonin on Healing Duration, Function and Pain Relief in Patients with Maxillofacial Fractures. A pilot study

Effect of Calcitonin on Healing Duration, Function and Pain Relief in Patients with Maxillofacial Fractures. A pilot study


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صفحه نخست سامانه
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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: جواد یزدانی , فرزین احمدپورپورناکی

کلمات کلیدی: Calcitonin, Intranasal, Maxillofacial Fracture

نشریه: , 4 , 7 , 2019

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله جواد یزدانی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده دندانپزشکی
کد مقاله 72175
عنوان فارسی مقاله Effect of Calcitonin on Healing Duration, Function and Pain Relief in Patients with Maxillofacial Fractures. A pilot study
عنوان لاتین مقاله Effect of Calcitonin on Healing Duration, Function and Pain Relief in Patients with Maxillofacial Fractures. A pilot study
ناشر 2
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق) Advances in Bioscience and Clinical Medicine
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح چهار – سایر سایت های تخصصی
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Introduction: Calcitonin is a polypeptide hormone regulating the metabolism calcium in the body. Many studies showed that calcitonin had analgesic effect on several painful circumstances. The aim of this study was to determine the effects of intranasal calcitonin during the immediate postoperative period on postoperative pain in patients undergoing maxillofacial fracture surgery. Materials and Methods: In this clinical trial which was conducted in April 2019 in Imam Reza Hospital of Tabriz, 16 patients with maxillofacial fracture were divided randomly into two groups. The intervention group was given 200UI of intranasal calcitonin and the control group received nasal spray of NaCl. The severity of pain was then evaluated daily for up to seven days after the operation, with the severity of: no pain (0) to the most severe pain (10) using visual analog scale for pain. The daily dose of analgesic was also measured. The patients were allowed to request 250 mg of injectable acetaminophen each day up to a maximum daily dose of 4 g (maximum permissible dose) in the event of pain. Results: The results show that the pain intensity between two groups was not significantly different. However in the seventh day the total acetaminophen consumption was significantly lower in the intervention group. Conclusion: calcitonin may be a useful medication to help to control the post operative pain by reducing the required dose of routine painkillers.

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نویسنده نفر چندم مقاله
جواد یزدانیاول
فرزین احمدپورپورناکیدوم

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