| Objective: In the current meta-analysis, we aimed to systematically review and summarize
eligible studies for the association between dietary inflammatory index (DII)
and blood pressure, hypertension (HTN) and glucose homeostasis biomarkers.
Design/Setting: In a systematic search of PubMed, Scopus and Google Scholar electronic
databases up to February 2019, relevant studieswere included in the literature
review. Observational studies evaluating the association between DII and HTN,
hyperglycaemia, systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting
blood glucose (FBG), insulin, homeostatic model assessment of insulin resistance
(HOMA-IR) and glycated Hb (HbA1c) were included.
Participants: Not applicable.
Results: Total numbers of studieswere as follows:OR for DII and HTN (n 12), OR for
DII and hyperglycaemia (n 9), HTN prevalence (n 9), mean (SD) of SBP and DII
(n 12), mean (SD) of DBP and DII (n 10), mean (SD) of FBS and DII (n 13), mean
(SD) of HbA1c and DII (n 3), mean (SD) of insulin and DII (n 6), mean (SD) of
HOMA-IR and DII (n 7). Higher DII scores were associated with higher odds of
HTN (OR = 1·13; 95 % CI 1·01, 1·27; P < 0·001), SBP (weighted mean difference
(WMD) = 1·230; 95 % CI 0·283, 2·177; P = 0·011), FBS (WMD = 1·083; 95% CI
0·099, 2·068; P = 0·031), insulin (WMD = 0·829; 95% CI 0·172, 1·486; P = 0·013),
HbA1c (WMD = 0·615; 95% CI 0·268, 0·961; P = 0·001) and HOMA-IR
(WMD= 0·192; 95 % CI 0·023, 0·361; P = 0·026) values compared with lowest DII
categories.
Conclusions: Lower inflammatory content of diets for prevention of cardiovascular
risk factors is recommended. |