Effects of chamomile tea on inflammatory markers and insulin resistance in patients with type 2 diabetes mellitus

Effects of chamomile tea on inflammatory markers and insulin resistance in patients with type 2 diabetes mellitus


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: مریم رف رف , محمد اصغری جعفرآبادی

کلمات کلیدی: type 2 diabetes mellitus, chamomile, inflammation, insulin resistance

نشریه: 0 , 1 , 3 , 2018

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله مریم رف رف
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات علوم تغذیه
کد مقاله 72029
عنوان فارسی مقاله Effects of chamomile tea on inflammatory markers and insulin resistance in patients with type 2 diabetes mellitus
عنوان لاتین مقاله Effects of chamomile tea on inflammatory markers and insulin resistance in patients with type 2 diabetes mellitus
ناشر 3
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق) trends in general practice
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس نشده
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Aim: The purpose of this study was to evaluate the effects of chamomile tea consumption inflammatory markers and insulin resistance in subjects with type 2 diabetes mellitus (T2DM). Methods: This single-blind randomized controlled clinical trial was conducted on 64 individuals with T2DM (males and females) aged between 30 and 60 years. The intervention group (n=32) consumed chamomile tea (3g/150 mL hot water) 3 times per day immediately after meals for 8 weeks. The control group (n=32) followed a water regimen for the same intervention period. Fasting blood samples, anthropometric measurements and 3-day, 24-h dietary recalls were collected at the baseline and at the end of the trial. Data were analysed by independent t test, paired t test, Pearson correlation test, and analysis of covariance. Results: Analysis of covariance showed that tumour necrosis factor-α (TNFα) and high sensitive C-reactive protein (hs-CRP) levels and homeostatic model assessment for insulin resistance (HOM-IR) were significantly decreased by 4.87%, 57.20% and 23.60% respectively in chamomile group compared with these variables in control group at the end of the intervention (all p<0.05). There was significant positive correlation between the changes of serum TNFα and hs-CRP with HOMA-IR (r=0.567, p<0.001 and r= 0.520, p<0.001, respectively) in chamomile tea group at the end of the study. Conclusion:: Short term intake of chamomile tea has beneficial effects on inflammatory markers and insulin resistance in patients with T2DM. Higher larger sample population and a longer intervention period may be required to show significant clinical improvements.

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نویسنده نفر چندم مقاله
مریم رف رفدوم
محمد اصغری جعفرآبادیسوم

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