| Aim: The aim of this study was to estimate the secondary malignancy risk from the radiation in FFB
prostate linac-based radiotherapy for different organs of the patient.
Background: Radiation therapy is one of the main procedures of cancer treatment. However, the application
the radiation may impose dose to organs of the patient which can be the cause of some malignancies.
Materials and methods: Monte Carlo (MC) simulation was used to calculate radiation doses to patient
organs in 18 MV linear accelerator (linac) based radiotherapy. A humanoid MC phantom was used to
calculate the equivalent dose s for different organs and probability of secondary cancer, fatal and nonfatal
risk, and other risks and parameters related to megavoltage radiation therapy. In out-of-field radiation
calculation, it could be seen that neutrons imparted a higher dose to distant organs, and the dose to
surrounding organs was mainly due to absorbed scattered photons and electron contamination.
Results: Our results showed that the bladder and skin with 54.89
×
10−3 mSv/Gy and 46.09
×
10−3 mSv/Gy,
respectively, absorbed the highest equivalent dose s from photoneutrons, while a lower dose
was absorbed by the lung at 3.42
×
10−3 mSv/Gy. The large intestine and bladder absorbed
55.00
×
10−3 mSv/Gy and 49.08
×
10−3, respectively, which were the highest equivalent dose s due to
photons. The brain absorbed the lowest out-of-field dose, at 1.87
×
10−3 mSv/Gy.
Conclusions: We concluded that secondary neutron portion was higher than other radiation. Then, we
recommended more attention to neutrons in the radiation protection in linac based high energy radiotherapy. |