Effectiveness of bacillus Calmette-Guerin vaccination history on pulmonary tuberculosis symptoms.

Effectiveness of bacillus Calmette-Guerin vaccination history on pulmonary tuberculosis symptoms.


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: صفر فرج نیا , خلیل انصارین , لیلا صاحبی

کلمات کلیدی: Bacillus Calmette–Guerin; Mycobacterium tuberculosis; Pulmonary tuberculosis; Symptoms; Vaccine effectiveness

نشریه: 0 , 0 , 0 , 2019

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نویسنده ثبت کننده مقاله خلیل انصارین
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات سل و بیماری های ریوی
کد مقاله 71639
عنوان فارسی مقاله Effectiveness of bacillus Calmette-Guerin vaccination history on pulmonary tuberculosis symptoms.
عنوان لاتین مقاله Effectiveness of bacillus Calmette-Guerin vaccination history on pulmonary tuberculosis symptoms.
ناشر 3
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق) Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Introduction: The aim of this study was to explore the effectiveness of BCG vaccination on the severity of clinical symptoms of pulmonary tuberculosis symptoms (PTb) in patients from the northwest and west of Iran. Materials and methods: In a cross sectional study of 358 patients with a diagnosis of PTb, 11 clinical symptoms, including cough, chest pain, dyspnea, sputum, fever, hemoptysis, weight loss, loss of appetite, wheezing, weakness, and fatigue were checked and patients with a score of six or more were placed in the severe clinical symptoms group. BCG vaccination scar and clinical symptoms were examined and recorded. Results: Of the subjects included in this study, 264 cases (73.7%) had no BCG vaccination scar. Comparison of the severity of clinical symptoms of PTb in patients with BCG vaccine history to those lacking vaccination history revealed lower symptom severity in patients who had been vaccinated (vaccine effectiveness = 95.5%; p < 0.00001). Conclusion: The results of this study may imply that Adjusting for age sex and smoking status, BCG vaccination decreases the severity of clinical symptoms in patients with PTb. We suggest performing a retrospective cohort study on a larger population. © 2019 Published by Elsevier Ltd.

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نویسنده نفر چندم مقاله
صفر فرج نیااول
خلیل انصاریندوم
لیلا صاحبیسوم

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