| Abstract
Background: Planning for obesity prevention is an important global health priority. Our aim
in this study was to find the optimal cut-off points of waist circumference (WC), waist- to- hip
ratio (WHR) and waist- to- height ratio (WHtR), as three anthropometric indices, for prediction
of overweight and obesity. We also aimed to compare the predictive ability of these indices to
introduce the best choice.
Methods: In this cross-sectional study, a total of 500 subjects were investigated. Anthropometric
indicators were measured using a standard protocol. We considered body mass index (BMI) as
the simple and most commonly used index for measuring general obesity as the comparison
indicator in the present study to assess the diagnostic value for other reported obesity indices.
We also performed receiver operating characteristic (ROC) curve analysis to define the optimal
cut-off points of the anthropometric indicators and the best indices for overweight and obesity.
Results: The proposed optimal cut-offs for WC, WHtR, and WHR were 84 cm, 0.48 and 0.78
for women and 98 cm, 0.56 and 0.87 for men, respectively. The area under the ROC curve of
WHtR (women: AUC=0.97, 95% CI: 0.96-0.99 vs. men: AUC=0.97, 95%CI: 0.96-0.99) and WC
(women: AUC=0.97, 95% CI, 0.95-0.99 vs. men: AUC=0.98, 95% CI: 0.97-0.99) were greater
than WHR (women: AUC=0.79, 95% CI =0.74-0.85 vs. men: AUC=0.84, 95% CI=0.79-0.88).
Conclusion: This study demonstrated that the WC and WHtR indicators are stronger indicators
compared to the others. However, further studies using desirable and also local cutoffs against
more accurate techniques for body fat measurement such as computerized tumor (CT) scans and
dual-energy x-ray absorptiometry (DEXA) are required. |