چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Background:Diffusion-weighted imaging (DWI) is a novel imaging technique with growing application in onco-imaging. This modality evaluates the diffusion of water molecules in various tissues, which is restricted in hypercellular regions such as malignant tissue. Apparent diffusion co-efficient (ADC) is a method which can quantify thedegree of restriction in tissues and can have diagnostic roles in characterization of hepatic lesions. In this study, 93patients with proven hepatic lesions were included. These patients had undergone initial evaluation viaultrasonography and dynamic CT scan, and had a definite diagnosis confirmed by biopsy. These patientsunderwent DW imaging and ADC values of their lesions were calculated. Patients were divided into two groups,benign and malignant groups, based on their biopsy results; and ADC values of hepatic lesions were compared inthe two groups.Results:The two groups were gender matched. There was a significant difference in the age distribution betweenthe two groups. Mean ADC values for benign and malignant hepatic lesions were 1.58 ± 0.35 (10-3mm2/s) and 0.87± 0.16 (10-3mm2/s), respectively. There was a statistically significant differences between benign and malignanthepatic lesions (pvalue < 10-3). DW imaging had a sensitivity of 97.6% and specificity of 98.7% in detectingmalignant hepatic lesions from benign ones (p= 0.0001, AUC = 0.99).Conclusion:DW MRI imaging can differentiate malignant and benign liver lesions with high sensitivity andspecificity using ADC values generated; furthermore, each subgroup of hepatic lesions could be determined basedon ADC values. |
| نویسنده | نفر چندم مقاله |
|---|---|
| رضا جواد رشید | اول |
| ابوالحسن شاکری باویل علیائی | دوم |
| محمد کاظم طرزمنی | سوم |
| رقیه رزاقی | چهارم |
| جواد جلیلی | پنجم |
| شهریار هاشم زاده | ششم |
| محمد میرزا آقازاده عطاری | هفتم |
| علی کیانی نظرلو | هشتم |
| آرمین زرین تن | نهم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 91130218(1).rar | 1399/05/04 | 4476099 | دانلود |
| 91130218(1).pdf | 1399/05/04 | 4849929 | دانلود |
| razzag.pdf | 1400/06/29 | 122482 | دانلود |
