چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Abstract: INTRODUCTION:Considering that a gluten-free diet (GFD) should be followed for life, investigating its effect on health is very important. In the present study, we systematically reviewed and meta-analyzed the studies that evaluated the changes in body mass index (BMI) and lipid profile during a gluten-free diet (GFD) in celiac patients. METHOD:The databases of Pubmed, Embase, Scopus, Web of Science and Cochrane Library were searched until June 2018 to select studies investigate the changes in BMI and lipid profile in celiac patients. The standard mean difference (SMD) was calculated. For the heterogeneity analysis, the I-square statistic test was used. RESULTS:Twenty-one articles were included in our systematic review and 16 studies were selected for meta-analysis. The results of meta-analysis showed the statistically significant increase in BMI [SMD: 0.26; 95% CI: 0.17, 0.35 p: <0.001] and HDL-C (HDL-C) [SMD: 0.36; 95% CI: 0.009, 0.18, p = 0.001] during GFD. However, the effect of GFD on total cholesterol [SMD: 0.17; 95% CI:–0.66, 0.41, p = 0.16], LDL-C [SMD: –0.21; 95% CI:–0.54, 0.10, p = 0.16], and triglyceride [SMD: 0.02; 95% CI:–0.22, 0.25, p = 0.87] was not statistically significant. CONCLUSION:The results of the present meta-analysis showed the positive effect of GFD on BMI and HDL-C. However, more cohort studies in this topic are needed with considering the level of mucosal healing and the effect of confounding factors such as physical activity level, smoking and dietary intakes on the association between GFD diet and cardiovascular risk factors. |
| نویسنده | نفر چندم مقاله |
|---|---|
| زینب نیک نیاز | اول |
| لیلا نیک نیاز | چهارم |
| حسین حسینی فرد | سوم |
| مهدیه عباسعلیزاد فرهنگی | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| nikniaz2019.pdf | 1398/12/14 | 574352 | دانلود |
