| خلاصه مقاله | Osteoarthritis (OA) is a chronic degenerative disease and an important reason of adult disability. There is no therapy for OA and there is no actual treatment to discontinue its progression. It is generally established that weight loss and physical activity form part of the non-pharmacological handling strategies for OA (1). Obesity increases strain on weight-bearing joints and, longitudinally, overweight and obese individuals are at significantly advanced risk for knee arthroplasty. Overweight/obese elderlies with OA in comparison with normal weight elderlies have more risk to develop pain and functional disabilities. There is indication that this happen because obesity is directly associated with inflammation, which leads to knee OA. An association of higher body mass index with the development of hand OA establishes an additional non-biomechanical role of obesity in OA (2). Furthermore, several studies have established that healthy nutrition can have a favorable role in OA. Different investigators have established a protector consequence of the Mediterranean diet in OA because of its anti-inflammatory nature. Although the confirmation for advantage of dietary-lipid modification (improved LC n-3 PUFA/diminished LC n-6 PUFA) and dropping of serum cholesterol on OA is presently slightly scarce, the recommendations suggested will at least help metabolic healthiness. So, nutritional status evaluation is desirable among subjects with OA as well as observing of alteration in body components, mainly the aging-related properties (3). Therefore, new intervention must be established to attain weight control of older subjects and proper body composition for assisting health promotion, enhancement of quality of life and decrease of OA effect in function of these patients. In this paper, the role of nutrition in OA is thoroughly discussed. |