چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Cancer is the second main reason of human deaths around the world. Developing accurate and effective techniques to the early stage diagnosis of cancer are very vital to start the treatment process. Targeted detection of the cancerous cell is the most reliable approach to the identification of cancer solid tumors. Folate receptor (FR) is overexpressed on the membrane of many types of cancers and is a fascinating molecule for targeting cancer because of the high affinity between FR and folic acid (FA) (Kd ≈ 10 pM). Such fact was extremely utilized to develop the imaging of solid tumors and targeted delivery of drugs. This review discusses the critical role of FRs for the quantitative recognition of cancer cells. In this regard, the applied advanced materials in the designing of the FR-based cytosensors and the state-of-art of the cytosensing devices were discussed that may be have possible uses as a device in the clinical diagnosis of various cancers. Also, the analytical performances and the favorable features of the reported methods were explored. The present review covers the reported FR-based methods for the detection of cancer cells from 2010 to 2019 and will be a useful reference for the future works. Moreover, the applications of FR-based strategy in cancer cells imaging were also discussed. |
| نویسنده | نفر چندم مقاله |
|---|---|
| جعفر سلیمانی | اول |
| محمد حسن زاده محله | دوم |
| محمد حسین صومی | چهارم |
| ابوالقاسم جویبان | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 218.pdf | 1398/11/28 | 4353346 | دانلود |
