Modulatory effect of photobiomodulation on stem cell epigenetic memory: a highlight on differentiation capacity.
Modulatory effect of photobiomodulation on stem cell epigenetic memory: a highlight on differentiation capacity.
نویسندگان: آرزو رضائی نژاد زمانی , شیرین صابریان پور , محمد حسین گرانمایه , فرهاد بانی , رضا رهبرقاضی
کلمات کلیدی: DNA methylation; Differentiation; Low-level laser irradiation; Stem cells
نشریه: 22723 , 2 , 35 , 2020
| نویسنده ثبت کننده مقاله |
رضا رهبرقاضی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز سلولهای بنیادی |
| کد مقاله |
71157 |
| عنوان فارسی مقاله |
Modulatory effect of photobiomodulation on stem cell epigenetic memory: a highlight on differentiation capacity. |
| عنوان لاتین مقاله |
Modulatory effect of photobiomodulation on stem cell epigenetic memory: a highlight on differentiation capacity. |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Differentiation potential of stem cells into various lineages makes these cells as promising sources to treat multiple diseases. In this regard, the use of different strategies and protocols to increase differentiation capacity is highly demanded. Low-level laser therapy, a relatively noninvasive technique, has the capacity to accelerate the healing of numerous injuries and a portion of restorative capacity could be correlated with the stem cell activation and differentiation. Several mechanisms have been diagnosed to participate in orientation of stem cells to functional mature cells. Among them, the status of DNA methylation orchestrates the maintenance of tissue-specific gene expression during the differentiation procedure. DNA methylation is a momentous event in embryogenesis and functional maturation. This review article highlighted the potency of laser irradiation (low-level intensities) in the differentiation of stem cells by modulation of methylation. The analysis of these modalities could help us to understand the underlying mechanisms participating in the therapeutic effects of photobiomodulation. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Zamani2020_Article_ModulatoryEffectOfPhotobiomodu.pdf | 1398/11/27 | 541813 | دانلود |