Iron oxide magnetic nanoparticles supported on amino propyl‐functionalized KCC‐1 as robust recyclable catalyst for one pot and green synthesis of tetrahydrodipyrazolopyridines and cytotoxicity evaluation
Iron oxide magnetic nanoparticles supported on amino propyl‐functionalized KCC‐1 as robust recyclable catalyst for one pot and green synthesis of tetrahydrodipyrazolopyridines and cytotoxicity evaluation
نویسندگان: سجاد عزیزی خواجه , جعفر سلیمانی , محمد حسن زاده محله
کلمات کلیدی: bioactive compounds, fibrous nano‐silica, magnetic nanoparticle, nano‐catalyst, tetrahydrodipyrazolopyridines.
نشریه: 2801 , 01 , 34 , 2020
| نویسنده ثبت کننده مقاله |
محمد حسن زاده محله |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات آنالیز دارویی |
| کد مقاله |
71130 |
| عنوان فارسی مقاله |
Iron oxide magnetic nanoparticles supported on amino propyl‐functionalized KCC‐1 as robust recyclable catalyst for one pot and green synthesis of tetrahydrodipyrazolopyridines and cytotoxicity evaluation |
| عنوان لاتین مقاله |
Iron oxide magnetic nanoparticles supported on amino propyl‐functionalized KCC‐1 as robust recyclable catalyst for one pot and green synthesis of tetrahydrodipyrazolopyridines and cytotoxicity evaluation |
| ناشر |
3 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| In this study, paramagnetic dendritic fibrous nano‐silica functionalized by aminopropyltriethoxysilan (Fe3O4@KCC‐1‐nPr‐NH2) was synthesized using a novel hydrothermal protocol and used as a highly efficient, recyclable and heterogeneous nanocatalyst for the synthesis of a wide range of tetrahydrodipyrazolopyridines derivatives (5a‐5 m). The influence of different reaction parameters, such as the effects of solvent, temperature, time and concentration of catalyst for the synthesis of tetrahydrodipyrazolopyridine (2a) were studied. This catalyst could be reused for ten consecutive recycles without any considerable loss in its catalytic activity. This novel synthesis method offers some advantages including short reaction time, high yield and simple work‐up procedure. Finally, the newly synthesized tetrahydrodipyrazolopyridines derivatives (5a‐5f) were characterized by 1H and 13C NMR, IR and CHN. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 216.pdf | 1398/11/22 | 1686941 | دانلود |
