Association of the mean platelet volume and red cell distribution width with dipper and non‑dipper blood pressure in prehypertensive non‑smokers

Association of the mean platelet volume and red cell distribution width with dipper and non‑dipper blood pressure in prehypertensive non‑smokers


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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: محمد رضا تابان صادقی , مسعود نوری وسکه

کلمات کلیدی: Blood pressure, Dipper, Mean platelet volume, Prehypertension, Red blood cell distribution width

نشریه: 5038 , 2019 , 12 , 2019

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نویسنده ثبت کننده مقاله مسعود نوری وسکه
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات ایمونولوژی
کد مقاله 71112
عنوان فارسی مقاله Association of the mean platelet volume and red cell distribution width with dipper and non‑dipper blood pressure in prehypertensive non‑smokers
عنوان لاتین مقاله Association of the mean platelet volume and red cell distribution width with dipper and non‑dipper blood pressure in prehypertensive non‑smokers
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح دو – PubMed
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Objective: Absence of nocturnal blood pressure (BP) dipping is associated with poor health outcomes, including increased mortality. Non-dipper BP seems to be a predictor of cardiovascular damage in hypertensive patients. The aim of this study was to investigate the association of the mean platelet volume (MPV) and red cell distribution width (RDW) with nocturnal dipping/non dipping status in newly diagnosed and untreated prehypertensive non-smokers, using ambulatory BP monitoring. Results: Twenty-eight patients (15 males) in the dipper group and 24 patients (11 males) in the non-dipper group were evaluated in this study. The age of patients was 41.64 ± 15.01 and 37.96 ± 15.08 years in the dipper and non-dipper groups, respectively. The rate of nocturnal systolic BP drop in the dipper and non-dipper groups was 13.79 ± 3.35% (10.20–22.10) and 5.96 ± 2.87% (1.10–9.30) (P < 0.001), respectively. Also, the mean rate of nocturnal diastolic BP drop in the dipper and non-dipper groups was 17.02 ± 5.09% (10.30–26.90) and 6.19 ± 2.75% (1.20–9.70) (P < 0.001), respectively. RDW and MPV were significantly higher in non-dipper patients than dipper patients (P = 0.001 and P = 0.012, respectively). Bivariate analysis revealed that MPV was inversely correlated with the nocturnal systolic BP drop (P = 0.005, r = − 0.385). Furthermore, RDW was inversely correlated with systolic BP drop (P = 0.019, r = − 0.324).

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نویسنده نفر چندم مقاله
محمد رضا تابان صادقیاول
مسعود نوری وسکهسوم

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