چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | انسیه سیدرضازاده دلالی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات سل و بیماری های ریوی |
| کد مقاله | 71092 |
| عنوان فارسی مقاله | Exhaled nitric oxide in overweight and obese asthma patients compared to normal weight asthmatic patients |
| عنوان لاتین مقاله | Exhaled nitric oxide in overweight and obese asthma patients compared to normal weight asthmatic patients |
| نوع ارائه | پوسترو سخنرانی |
| عنوان کنگره / همایش | European Respiratory Society International Congress 2019 |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Spain |
| شهر محل برگزاری کنگره/ همایش | Madrid |
| سال انتشار/ ارائه شمسی | 1398 |
| سال انتشار/ارائه میلادی | 2019 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1398/07/06 الی 1398/07/10 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://erj.ersjournals.com/content/54/suppl_63/PA2611 |
| آدرس علمی (Affiliation) نویسنده متقاضی | 4Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| خلیل انصارین | اول |
| انسیه سیدرضازاده دلالی | دوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Biomarkers, Asthma - mechanism, Nitric oxide |
| خلاصه مقاله | Abstract Introduction: The differences in phenotypes of the asthma are increasingly recognized with potential implications in treatments of these phenotypes. We investigated the difference in exhaled nitric oxide (eNO) level in patients with obese and non-obese asthmatics. Materials and Methods: 135 patients with asthma without prior history of treatment with inhaled or systemic steroids were selected from a respiratory subspecialty clinic in Tabriz, Iran. After full history and physical examination all patients had eNO measurement (using NObreath provided by Bedfont, UK) and spirometry (using Jaeger spirometer, Germany) performed with standard techniques. The level of eNO compared in asthma patients from different BMI groups and also the correlation of the eNO with different parameters of pulmonary function was analyzed. Results: The eNo levels in overweight and obese asthmatics with BMI of 25 kg/m2 or higher were significantly lower than asthma patients with BMI less than 25 kg/m2( 44.1 ppb versus 63.9 ppb respectively; p< 0.05) and the level of eNO correlated negatively with BMI of all subjects with asthma( r= - 0.18; p< 0.05). Conclusion and Clinical Implications: These findings indicates that eNO is lower in overweight and obese asthmatic patients with associated metabolic and mitochondrial changes compared with normal weight asthmatics and this is in line with possible differences in disease mechanisms with potential clinical implications of varied efficacy of drugs in these phenotypes of asthma. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Untitled.2.png | 1398/11/16 | 113078 | دانلود |
| Untitled.jpg | 1398/11/16 | 119846 | دانلود |
