چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| رامین قاسمی شایان | اول |
| داود خضرلو | دوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | FDG PET scan, Pitfalls, Cancer |
| خلاصه مقاله | Background Nowadays, PET/CT has a major role in early cancer detection and management of cancer treatment. FDG PET/CT has become essential in evaluating cancer patients in major medical centers throughout the world. Unfortunately, FDG is not a cancer-specific agent, so, despite the high sensitivity of FDG PET/CT, there are false negative results due to high FDG uptake in normal tissues, which are called pitfalls. So pitfalls arise when real benign biologic processes result in imaging findings that mimic malignancy. Methods: 1- Some of the most common pitfalls in FDG PET/CT are inflammatory and infectious processes. Granulomatous diseases, Foreign Body Reaction, Thrombosis, bacterial pneumonia, diverticulitis, abscess, and mastitis. 2- Trauma and healing is another way of creating pitfalls. First, Injury, FDG activity is progressively reduced while healing progresses to completion. In some difficult cases, follow-up PET/CT is often helpful. Common etiologies include fractures, muscle and ligament strains, lacerations and hematomas. Second, Post-Surgical such as Post-operative fractures, heterotopic ossification, and infection. Surgical placement of anything through the skin, such as catheters, ports, and stomas cause prolonged moderate FDG activity. 3- Physiologic variation is another way of creating pitfalls. Physiologic FDG activity varies widely in certain normal tissues with respect to time, location, and intensity. The most common pitfalls are seen in cardiac muscle, brown fat, the gastrointestinal tract, the genitals, the uterine lining, breast tissue, skeletal muscle, and the central nervous system. 4- Anatomic variations, both normal and abnormal, can and do lead to interpretation errors. Key to avoiding this pitfall is to note the elongation of activity in the cranial caudal direction on the MIP images. Duplicated collecting systems, bladder diverticula, and transurethral resection of prostate (TURP) defects filled with urine are other common pitfalls. 5- Hematopoietic is another kind of pitfalls. Chronic severe anemia, such as is seen with thalassemia, can result in expansion of normal bone marrow FDG activity into the appendicular skeleton. 6- The last kind of pitfalls is Drug related pitfall. Abnormally high diffuse bone marrow FDG activity is commonly seen in patients who have recently received granulocyte or granulocyte–macrophage colony stimulating factors. Conclusion Unfortunately, FDG is not a cancer-specific agent, so for clinical judgment the history of patient should be considered as well as CT image and raw PET images should be reviewed. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Pit falls.jpg | 1398/11/16 | 275170 | دانلود |
| Pitfalls in PET Scan2 (1).docx | 1398/11/16 | 15114 | دانلود |
