Cell junction proteins: Crossing the glomerular filtration barrier in diabetic nephropathy
Cell junction proteins: Crossing the glomerular filtration barrier in diabetic nephropathy
نویسندگان: عزیز افتخاری , سپیده زنونی واحد , محمد رضا اردلان , الهام احمدیان , سید مهدی حسینی یان خطیبی
کلمات کلیدی: Slit diagramsPodocytesDiabetic nephropathyGap junctionsTight junctions
نشریه: 15044 , 1April , 148 , 2020
| نویسنده ثبت کننده مقاله |
محمد رضا اردلان |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کلیه |
| کد مقاله |
70896 |
| عنوان فارسی مقاله |
Cell junction proteins: Crossing the glomerular filtration barrier in diabetic nephropathy |
| عنوان لاتین مقاله |
Cell junction proteins: Crossing the glomerular filtration barrier in diabetic nephropathy |
| ناشر |
10 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Diabetic nephropathy as a deleterious complication of diabetes mellitus and an important cause of end-stage renal failure is characterized by changes in the molecular and cellular levels. Cell-cell communication via the gap and tight junctions are involved in the pathogenesis of diseases such as diabetes and kidney failure. Studying cell junctions including gap junctions, tight junctions, and anchoring junctions within the nephron can be used as an early sign of diabetic nephropathy. Furthermore, cell junctions may be an upcoming target by pharmacological methods to improve treatments of diabetic nephropathy and pave the way to introduce promising therapeutic strategies based on cell-cell communications effects and its translation into clinical studies for the treatment of diabetic nephropathy. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 1-s2.0-S0141813019383643-main.pdf | 1398/11/05 | 997261 | دانلود |