Combination Effect of Voluntary Exercise and Garlic (Allium sativum) on Oxidative Stress Biomarkers and Lipid Profile in Healthy Rats

Combination Effect of Voluntary Exercise and Garlic (Allium sativum) on Oxidative Stress Biomarkers and Lipid Profile in Healthy Rats


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پژوهان
صفحه نخست سامانه
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چکیده مقاله
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نویسندگان
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دانلود مقاله
دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: فریبا قیاسی

کلمات کلیدی: -Garlic -Voluntary exercise -Oxidative stress -Lipid profile

نشریه: 27161 , 3 , 25 , 2019

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله فریبا قیاسی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات کاربردی دارویی
کد مقاله 70736
عنوان فارسی مقاله Combination Effect of Voluntary Exercise and Garlic (Allium sativum) on Oxidative Stress Biomarkers and Lipid Profile in Healthy Rats
عنوان لاتین مقاله Combination Effect of Voluntary Exercise and Garlic (Allium sativum) on Oxidative Stress Biomarkers and Lipid Profile in Healthy Rats
ناشر 3
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Short Communication
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background: We evaluated the combination effect of voluntary exercise and garlic on serum oxidative stress biomarkers and lipid profile in healthy rats. Methods: The rats were randomly assigned to four groups (n=7): Control, Garlic, Exercise, and Garlic + Exercise. Rats were fed with raw fresh garlic homogenate by oral gavage (250 mg/kg) or were subjected to voluntary exercise using stainless steel running wheels alone or together for 6 weeks. The samples were collected at the end of the experiment. Results: After 6 weeks, total cholesterol, low-density lipoprotein (LDL), triglycerides (TG) and high-density lipoprotein (HDL) levels improved in both garlic and exercise group, compared with the control group. We also found that serum glutathione peroxidase (Gpx), Superoxide dismutase (SOD), Catalase (CAT), and Total antioxidant (TAC) levels enhanced significantly following the above-mentioned interventions. Furthermore, simultaneous treatment of rats with garlic and voluntary exercise had an additive effect on these parameters. However, malondialdehyde (MDA) level was not significantly different from the control group during our protocol. Conclusion: The findings revealed that simultaneous treatment of rats with garlic and voluntary exercise improved antioxidant defense system and lipid profile in an additive manner in healthy rats.

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فریبا قیاسیاول

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Combination Effect of Voluntary Exercise and Garlic (Allium sativum) on.pdf1398/10/21430527دانلود