Multifunctional aptasensors based on mesoporous silica nanoparticles as an efficient platform for bioanalytical applications: Recent advances

Multifunctional aptasensors based on mesoporous silica nanoparticles as an efficient platform for bioanalytical applications: Recent advances


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نویسندگان: پریا پاشازاده , محمد حسن زاده محله

کلمات کلیدی: Mesoporous silica nanoparticles, Aptamer, Biosensor, Cancer therapy, Biomedical analysis, Advanced nanomaterials

نشریه: 33720 , 1 , 124 , 2020

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نویسنده ثبت کننده مقاله محمد حسن زاده محله
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات آنالیز دارویی
کد مقاله 70718
عنوان فارسی مقاله Multifunctional aptasensors based on mesoporous silica nanoparticles as an efficient platform for bioanalytical applications: Recent advances
عنوان لاتین مقاله Multifunctional aptasensors based on mesoporous silica nanoparticles as an efficient platform for bioanalytical applications: Recent advances
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نوع مقاله Review Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Mesoporous silica nanoparticles (MSNs) are an essential and inseparable part of scientific application in today's world. These materials garnered more attention, in biosensing, catalysis, bioimaging, energy storage, and disease diagnosis due to their privileged futures. The unique physiochemical properties have been made these nanomaterials an excellent candidate for drug delivery applications as well as electrochemical and optical biosensing. MSNs are able to encapsulate enormous materials in their structural pores and deliver those materials to target, more meticulously. Aptasensor is type of biosensors that use aptamer for increasing selectivity and sensitivity. These are capture by nanomaterials by covalent and non-covalent linking for many different purpose such as diagnosis and target therapy. The aim of this review is introducing the most recent research progress on aptasensors based on MSNs, including various optical and electrochemical aptasensors, their strategy, and procedure, limit of detection, as well as their advantages and limitation. Moreover, different types of aptasensors based on MSNs is highlighted in this review for targeting and treatment of cancer cells. Although encouraging and interesting investigations have been achieved in this filed, design and mass production and effective biological application of aptasensors and MSNs based aptasensors are still challenging.

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نویسنده نفر چندم مقاله
پریا پاشازادهسوم
محمد حسن زاده محلهچهارم

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