چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سولماز فلاحی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | کمیته تحقیقات دانشجویی |
| کد مقاله | 70600 |
| عنوان فارسی مقاله | بررسی نقش سد خونی مغزی در بیماری مالتیپل اسکلروزیس |
| عنوان لاتین مقاله | The role of blood brain barrier in multiple sclerosis |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | کنگره علوم اعصاب پایه و بالینی |
| نوع کنگره / همایش | ملی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1398 |
| سال انتشار/ارائه میلادی | 2019 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1398/09/27 الی 1398/09/29 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | www.bcnc.ir |
| آدرس علمی (Affiliation) نویسنده متقاضی | Student research committee, Tabriz university of medical sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| سولماز فلاحی | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Abstract: Introduction: For all materials not easily commute to our central nervous system, A barrier known as the blood-brain barrier is built for our brain. Various studies have been done on the role of BBB in MS. Method: Various databases such as google scholar, Pub Med and Science direct were reviewed and 70 papers were selected. Of these, 40 articles were selected as the main essay for writing this review. Result: Vascular endothelial cells in the walls of this region are quite compact together. We say that the so-called tight junctions. The system is to ensure that potentially harmful toxins, infectious agents and immune cells cannot enter the central nervous system. But the material that is necessary for normal brain metabolism, such as glucose and oxygen are able to cross this barrier, Carbon dioxide as a metabolite of brain metabolism is able to cross this barrier so. In MS following the destruction of the blood-brain barrier, damaging factors including white blood cells are able to pass through it. Due to the lack of specify of white blood cells to brain neurons, myelin antigens and oligodendrocytes are detected as foreign agents. And so they began to destroy them. The present paper is to examine the role of the blood-brain barrier in MS pathophysiology. Conclusion: In MS, endothelial cells leading to the formation of the tight junctions is to be demolished. So disrupting of BBB could be one of the most important factors in MS pathology. Keywords: blood brain barrier - multiple sclerosis |
| کلمات کلیدی | Keywords: blood brain barrier - multiple sclerosis |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 1full.docx | 1398/11/23 | 14522 | دانلود |
| 2full.docx | 1398/11/23 | 15962 | دانلود |
| M.jpg | 1398/11/19 | 3206627 | دانلود |
| TTT.pdf | 1398/11/19 | 28477 | دانلود |
| TT.jpg | 1398/11/19 | 20249 | دانلود |
| BBB.PNG | 1398/10/08 | 105316 | دانلود |
| poster.PNG | 1398/10/08 | 497991 | دانلود |
