چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Backgrounds: Obesity is associated with numerous chronic diseases. The current study was aimed at investigating the effects of Spirulina platensis on Macrophage inhibitory cytokine 1 (MIC-1), biomarkers of oxidative stress and anthropometric features in obese patients. Methods: Fifty six obese individuals, aged between 20–50 years old, participated in the current trial and were randomly allocated into two groups of intervention and control receiving either Spirulina platensis or a placebo daily for 12 weeks, respectively. Changes in serum and blood concentrations of MIC-1, markers of oxidative stress and anthropometric features were evaluated at baseline and after the intervention period. Appetite was also measured by visual analogue scale (VAS). Results: Spirulina platensis treatment for 12 weeks significantly reduced MIC-1 concentrations and appetite in obese individuals (P < 0.05); whereas no change was observed in the placebo-treated group. Moreover, Spirulina platensis significantly increased blood concentrations of superoxide dismutase (SOD) and attenuated anthropometric parameters (P < 0.05). Although these changes were also observed in the placebo-treated group, the changes in Spirulina platensis treated group was significantly greater than with placebo- treated group. Conclusion: Considering the beneficial therapeutic effects of Spirulina platensis in attenuating anthropometric parameters and reducing oxidative stress, it can be suggested as a complementary therapeutic approach to obesity and related disorders. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهدیه عباسعلیزاد فرهنگی | دوم |
| عاطفه شریعت | اول |
| ریحانه زینلیان | سوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| PDF.pdf | 1398/09/23 | 978167 | دانلود |
| TAAHOD.doc | 1398/09/23 | 48128 | دانلود |
