Echocardiographic Evaluation of the Relationship Between inflammatory factors (IL6, TNFα, hs-CRP) and Secondary Pulmonary Hypertension in patients with COPD. A Cross sectional study
Echocardiographic Evaluation of the Relationship Between inflammatory factors (IL6, TNFα, hs-CRP) and Secondary Pulmonary Hypertension in patients with COPD. A Cross sectional study
نویسندگان: خلیل انصارین , فرید رشیدی , حسین نامدار , اکبر شریفی , محمدرضا غفاری باویل
کلمات کلیدی: COPD, pulmonary hypertension,inflammatory factors, secondary
نشریه: 0 , 4 , 63 , 2015
| نویسنده ثبت کننده مقاله |
حسین نامدار |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات قلب وعروق |
| کد مقاله |
70382 |
| عنوان فارسی مقاله |
Echocardiographic Evaluation of the Relationship Between inflammatory factors (IL6, TNFα, hs-CRP) and Secondary Pulmonary Hypertension in patients with COPD. A Cross sectional study |
| عنوان لاتین مقاله |
Echocardiographic Evaluation of the Relationship Between inflammatory factors (IL6, TNFα, hs-CRP) and Secondary Pulmonary Hypertension in patients with COPD. A Cross sectional study |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح دو – PubMed |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| play a major role in the pathogenesis of various types
of human pulmonary hypertension such as idiopathic
PAH (IPAH) and PAH associated’’ with connective tissue
disease. Although we know that inflammatory factors
such as IL6 and TNFα have an important role in IPAH, there
is limited information about the relationship between
acute phase reactants and pulmonary hypertension
occurring secondary to pulmonary diseases such as
chronic obstructive pulmonary diseases (COPD).
Methods: This cross-sectional study was carried
out on 94 patients who had COPD. Patients with a
recent history of systemic steroid and acetylsalicylic
acid ( ASA) use, infection, trauma or surgery,
gastrointestinal bleeding, coronary artery disease
(CAD) and Hypertension were excluded. Body
plethysmography and transthoracic echocardiography
were done. Blood samples for each patient included
were drawn for complete blood count (CBC), IL6, TNFα
and highly sensitive C reactive protein (hs-CRP).
Results: Twenty patients (28.6%) had pulmonary
hypertension. The difference between the mean IL6
and hs-CRP in patients with and without pulmonary |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
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