| خلاصه مقاله | Introduction: rheumatic fever (RF) is an inflammatory connective tissue disease that involves multiple organs such as joints, brain and especially heart. Considering the importance and destroying pattern of RF and imposition if huge costs in order to fully restore the person to normal. Life, which fails to fully restore the effects of disease, carrying out basic studies about prevalence of cardiac involvement to manage disease properly and doing rehabilitation therapies to restore to restore the patient to normal life is necessary. On the other hand, the search results showed that a comprehensive study wasn't done about the cardiac involvement in Acute RF. The purpose of this study was to investigate the prevalence of cardiac involvement in the patients with acute rheumatic fever during the last 10 years.
Methods: First, in coordination with the medical evidence unit, the list of patients admitted with RF is being prepared in pediatrics hospital for the last 10 years. It is to be mentioned that the only cases of the last the only cases of the last 10 years have been examined because of the restriction to access to cases before mentioned years. We will take the information we need (including cardiac involvement of acute rheumatic fever and demographic information of patients) according to the check list that we prepared previously.
Results: In the study of 48 patients with acute rheumatic fever, who were
hospitalized over the last 10 years, 35 patients (72/9%) had cordites 36 patients (73%) had arthritis. The most common valvular involvement was mitral valve regurgitation (66/7%) then aortic valve insufficiency (35/5%) and after them,
mitral and aortic valves regurgitation simultaneously. Serum titer of Anti-streptolysin O (ASO) during hospitalization and the medical treatment was slowly decreasing and the highest serum liter of that was while admission. There was no significant connection between carditis with probability of age, sex, body weight, rheumatic arthritis, socioeconomic level of family, valvlar disease of ASO serum liter.
Conclusion: The finding of this study showed that heart complications such as carditis with high incidence of over 70% were associated with acute RF disease. There was no significant correlation among other signs of this disease of other variables of this study with probability of carditis. Noting that Middle East is among the high prevalence and incidence of acute RF and Iran is not an exception, so long term screening and follow up of carditis in acute RF patients is necessary. We can’t deny that by diagnosing and proper treating of the streptococcal. Phareyngitis, we can prevent acute RF and its long term complications such as carditis and the other complications of that disease. |