چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Objective: Urinary tract infections (UTIs) are the most common infectious diseases, and Escherichia coli is the most common pathogen isolated from patients with UTIs. The products of sfa, afa and foc genes are important for binding of the bacterium to urinary tract epithelium. Our aim was to investigate these genes in E. colis isolated from patients with UTIS. The frequencies of the genes were determined using PCR. Bioflm formation and antibiotic resistance rates were determined using microtiter plate and disk difusion methods, respectively. The P < 0.05 was considered statistically signifcant. Results: The frequencies of sfa, afa and foc were 75.3%, 17.5% and 22.5%, respectively showing a signifcantly higher prevalence of the sfa gene. The most efective antibiotics against the E. colis were nitrofurantoin and amikacin. The highest microbial resistance rates were also observed against amoxicillin and ampicillin. Furthermore, 12.7%, 6.3%, 74.7% and 6.3% of the isolates showed strong, moderate, weak capacities and no connections to form bioflms, respectively. The expression of the sfa gene was signifcantly associated with forming strong bioflms. Regarding the variabilities in the characteristics of E. coli strains associated with UTIs, it seems reasonable to adjust diagnostic and therapeutic methods according to the regional microbial characteristics |
| نویسنده | نفر چندم مقاله |
|---|---|
| لیلا واحدی | سوم |
| امین خامنه | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| s13104-019-4825-8.pdf | 1398/09/17 | 857788 | دانلود |
