| Prevalence of metabolic syndrome (MetS), as a major health problem, is increasing.
Very limited data exist on the effect of Cuminum cyminum L. essential oil (CuEO) on
MetS components. Accordingly, this study aimed to examine the effect of CuEO
supplementation on anthropometric indices, glycemic control, blood pressure, lipid
profile, and insulin resistance in patients with MetS. In a randomized, triple‐blind,
placebo‐controlled clinical trial, 56 patients with MetS aged 18–60 years received
either 75 mg CuEO or placebo soft gel thrice daily for 8 weeks. Anthropometric indices
and biochemical measurements were assessed at baseline and end of the study.
At the end of study, except for diastolic blood pressure (DBP), the other assessed variables
were not significantly different between two groups. In intra group analysis, placebo and CuEO groups both had nonsignificant decrements in DBP (mean difference
[MD] with 95% CI: −3.31 [−7.11, 0.47] and −1.77 [−5.95, 2.40] mmHg, respectively).
However, DBP was significantly lower in CuEO compared with the placebo
group at the end of study (81.41 ± 5.88 vs. 84.09 ± 5.54 mmHg, MD with 95% CI:
−3.98 [−7.60, −0.35] mmHg, p < .05). The results indicated that CuEO does not have
any effect on MetS components, except for DBP in patients with MetS. |