Experimental and computational approaches for measuring minoxidil solubility in propylene glycol + water mixtures at different temperatures
Experimental and computational approaches for measuring minoxidil solubility in propylene glycol + water mixtures at different temperatures
نویسندگان: الهه رحیم پور , ابوالقاسم جویبان
کلمات کلیدی: Minoxidil
Propylene glycol
Solubility
Jouyban-Acree model
Thermodynamic properties
Preferential solvation
نشریه: 18106 , 0 , 280 , 2019
| نویسنده ثبت کننده مقاله |
ابوالقاسم جویبان |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات آنالیز دارویی |
| کد مقاله |
70236 |
| عنوان فارسی مقاله |
Experimental and computational approaches for measuring minoxidil solubility in propylene glycol + water mixtures at different temperatures |
| عنوان لاتین مقاله |
Experimental and computational approaches for measuring minoxidil solubility in propylene glycol + water mixtures at different temperatures |
| ناشر |
7 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Minoxidil solubility in binary mixtures of propylene glycol + water at different temperatures has been performed by shake-flask method followed by spectrophotometry method. Four cosolvency models including the
modified Wilson model, the Yalkowsky model, Jouyban-Acree model and Jouyban-Acree-van't Hoff model
were used to correlate the measured solubility data. The correlation and prediction abilities of these models
were compared by computing mean relative deviations (MRD%). Apparent thermodynamic properties of minoxidil dissolution such as enthalpy, entropy and Gibbs free energy were investigated through van't Hoff and Gibbs
equations. Furthermore, preferential solvation parameters of minoxidil were calculated by means of the inverse
Kirkwood-Buff integrals. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 3.pdf | 1398/09/13 | 518149 | دانلود |
