Cutaneous and post kala-azar dermalleishmaniasis caused byLeishmania infantumin endemic areas of visceral leishmaniasis,northwestern Iran 2002–2011: a case series
Cutaneous and post kala-azar dermalleishmaniasis caused byLeishmania infantumin endemic areas of visceral leishmaniasis,northwestern Iran 2002–2011: a case series
نویسندگان: احمد کوشا
کلمات کلیدی: Cutaneous leishmaniasis, Visceral leishmaniasis, Leishmania infantum, Post kala-azar dermal leishmaniasis, Nested-PCR, Iran
نشریه: 26792 , 4 , 107 , 2013
| نویسنده ثبت کننده مقاله |
احمد کوشا |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده بهداشت |
| کد مقاله |
70212 |
| عنوان فارسی مقاله |
Cutaneous and post kala-azar dermalleishmaniasis caused byLeishmania infantumin endemic areas of visceral leishmaniasis,northwestern Iran 2002–2011: a case series |
| عنوان لاتین مقاله |
Cutaneous and post kala-azar dermalleishmaniasis caused byLeishmania infantumin endemic areas of visceral leishmaniasis,northwestern Iran 2002–2011: a case series |
| ناشر |
11 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Visceral leishmaniasis (VL) is endemic in Northwest and southern Iran. Reports of cutaneous leishmaniasis
(CL) in Northwest areas are rare, and its etiological agents are unknown. In the current study, we report six
CL and two post kala-azar dermal leishmaniasis (PKDL) cases caused by Leishmania infantum from
endemic areas of VL in the Northwest. Smears were made from skin lesions of 30 suspected patients in
2002–2011, and CL was determined by microscopy or culture. Leishmania spp. were identified by nested-
PCR assay. The disease was confirmed in 20 out of 30 (66%) suspected patients by parasitological
examinations. L. infantum was identified in eight and Leishmania major in 12 CL cases by nested-PCR.
Cutaneous leishmaniasis patients infected with L. major had the history of travel to CL endemic areas. L.
infantum antibodies were detected by direct agglutination test (DAT) at titers of 1:3200 in two cases with
history of VL. Results of this study indicated that L. infantum is a causative agent of CL as well as PKDL in
the VL endemic areas. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| pgh-107-04-194.pdf | 1398/09/13 | 179385 | دانلود |