چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Background: Different additives have been used to prolong regional blockade. We designed a prospective, randomized, double-blind, controlled clinical trial to evaluate the effect of dexamethasone added to bupivacaine-fentanyl on the duration of postoperative analgesia via epidural catheterization. Methods: Seventy two adult patients scheduled for elective abdominal or thoracic surgery under epidural anesthesia were randomly allocated into two groups to receive either bupivacaine (0.5%) - fentanyl (50μg) and dexamethasone (8 mg) in lumbar or thoracic epidural anesthesia (Dexa group, n=36), or bupivacaine-fentanyl and saline normal (control group, n=36) via epidural catheter. Duration of analgesia, postoperative pain score and IV analgesic use at first 24 hours were recorded and compared. Results: Two patients were excluded (one in each group) due to unsuccessful blockade. Age, gender and duration of surgery were similar in the two groups (p>0.05). The duration of analgesia (372±58.1vs. 234.6±24.3 min) was significantly longer and pain score and pentazocine use were less in the Dexa than the control group (37.1± 19.7 mg v.s. 73.1 ± 17.6 mg, respectively; p=0.001). Conclusions: This study revealed that dexamethasone added to bupivacaine-fentanyl solution in epidural analgesia prolongs the duration of analgesia in abdominal or thoracic surgery. |
| نویسنده | نفر چندم مقاله |
|---|---|
| بهمن نقی پور باسمنج | اول |
| داود آقا محمدی | دوم |
| رسول آذرفرین | سوم |
| میر موسی میری نژاد | چهارم |
| عیسی بیله جانی | پنجم |
| عباسعلی درستی | ششم |
| صمد اسلام جمال گلزاری | هفتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| O-Dexa epidural.pdf | 1398/09/10 | 231077 | دانلود |
