| Objectives This study sought to evaluate the outcomes of endovascular treatment with covered
versus bare Cheatham-platinum stents (NuMed, Hopkinton, New York) in coarctation of aorta (CoA)
patients.
Background Covered stenting has been newly recognized as a useful therapeutic method for patients
with native CoA, but there has been no study comparing the use of covered stents with bare stents for
treating CoA.
Methods In this randomized clinical trial, 120 patients with a mean age of 23.60 10.99 years (range
12 to 58 years, 79 men), with post-ductal, short-segment, severe native CoA underwent implantation of
bare Cheatham-Platinum (bCP) (n ¼ 60) or covered Cheatham-Platinum (cCP) (n ¼ 60) stents. Patients
were followed clinically at 1, 3, 6, and 12 months after the stenting and yearly thereafter. During
follow-up, multislice computed tomography (64 slices) was scheduled to assess any complications.
Results The procedural success rate was 100% in both groups. Patients were followed for 31.1
19.2 months. Although recoarctation was seen only in the bCP group during follow-up, the difference
between groups did not reach statistical significance (6.7%vs. 0%; p ¼ NS). Two cases of pseudoaneurysm
(3.3%) occurred in the cCP group, but none was observed in the bCP group (p ¼ NS). Normotensive
status significantly increased during follow-up in both groups (from 15% to 73.3% in the bCP group
and 16.7% to 78.3% in the cCP group, p < 0.001 for each group and not significant between groups).
Conclusions Implanting bCP and cCP stents have very high success rates with remarkable
hemodynamic effects in severe native CoA patients. Patients undergoing cCP stent implantation
experienced a nonsignificantly lower recoarctation rate and a higher occurrence of pseudoaneurysm
formation with respect to bCP stenting during follow-up. These findings indicate that CoA stenting
is a safe procedure. (Endovascular Stenting With Covered CP Stent Compared With Bare CP Stent
for Adult Patients With Coarctation: The Initial and Intermediate-Term Follow-Up Results;
IRCT201012045311N1) (J Am Coll Cardiol Intv 2014;7:416–23) ª 2014 by the American College
of Cardiology Foundation |