چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | یودا یعقوبی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | کمیته تحقیقات دانشجویی |
| کد مقاله | 69928 |
| عنوان فارسی مقاله | تأثیر اگزوزوم مشتق از سلولهای بنیادی مزانشیمی بند ناف انسان بر بهبود زخم و ترمیم بافت |
| عنوان لاتین مقاله | The Effect of Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosome on Wound Healing and Tissue Repair |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | 4th International Congress and 6th National Congress of Wound and Tissue Repair (The Future of Wound and Oscars) |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1398 |
| سال انتشار/ارائه میلادی | 2019 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1398/08/28 الی 1398/09/01 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://www.wtrc.ir/en |
| آدرس علمی (Affiliation) نویسنده متقاضی | Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| یودا یعقوبی | اول |
| مجید زمانی | دوم |
| مهدی یوسفی | سوم |
| علی اکبر موثق پور اکبری | چهارم |
| امیر مهدی زاده حقیقی | پنجم |
| علیرضا پیش گاهی | ششم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | The Effect of Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosome on Wound Healing and Tissue Repair In wound healing and tissue regeneration, coordination of many factors such as migration, proliferation, differentiation, cell growth and apoptosis regulation in the damaged tissue cells is essential. Mesenchymal stem cells (MSCs) and exosomes derived from these cells markedly enhance the damaged tissue repair. Umbilical cord is one of the most suitable and available sources of MSCs because of its stronger capacity to differentiation, low infections transmission risk (especially cytomegalovirus) and no need for high compatibility of human leukocyte antigens between donor and recipient. Exosomes have different factors such as growth factors, cytokines, signaling lipids, regulatory miRNAs and mRNAs that can play a role in damaged tissues repair. In recent years, the use of human umbilical cord mesenchymal stem cells-derived exosome (HUCMSC-EXO) has attracted much attention for the treatment of various diseases including liver, kidney, cardiovascular, Alzheimer’s disease, and nerve and spinal cord injury. Studies have shown that HUCMSC-EXO influences Wnt/βcatenin and 14-3-3ζ/YAP signaling pathways affecting cell proliferation and migration, apoptosis regulation and inflammation reduction causing increased re-epithelialization, damaged skin tissue repair, and cutaneous regeneration. Therefore, HUCMSC-EXO can be considered as a new cell-free therapeutic and a good source for wound healing and nerve tissue repair without tumorigenicity and immunogenicity concerns. |
| کلمات کلیدی | Umbilical cord Mesenchymal stem cells, Exosome, Wound healing, Tissue repair, Regenerative medicine |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| certificate of poster presentatioin.jpg | 1398/09/02 | 1043504 | دانلود |
| WJ Abstract Book.jpg | 1398/09/02 | 258307 | دانلود |
| Abstract.pdf | 1398/09/03 | 290616 | دانلود |
| Poster.pdf | 1398/09/03 | 2273656 | دانلود |
| 1.docx | 1398/09/03 | 14688 | دانلود |
| 2.docx | 1398/09/03 | 15982 | دانلود |
| ticket tabriz-tehran.pdf | 1398/09/05 | 954094 | دانلود |
| tiket tehran-tabrize.pdf | 1398/09/05 | 899004 | دانلود |
