| Objective: To investigate the effect of cognitive behavioral therapy on anxiety and depression
in infertile women.
Methods: This study was performed in 2019 by searching Google Scholar, Scopus, PubMed/
MEDLINE, Cochrane library, EMBASE, Proquest, ISI Web of Science, MagIran, SID and
IranMedex. Eligible studies were selected by two reviewers and outcomes of interest were
extracted. The meta-analysis was performed using the random effect models.栺- square statistic
test was used for heterogeneity analysis. Presence of publication bias was also checked.
Results: Eleven studies were included in this review. Between-group differences (cognitive
behavioral therapy and control groups) in risk ratio for infertile women’s depression was
d=-1.36; 95% CI=-1.81, -0.90; P<0.001. For infertile women’s anxiety, between-group
differences in risk ratio was d= -0.83; 95% CI= -1.18, -0.47; P<0.001.
Conclusions: Cognitive behavioral therapy is effective in the reduction of depression and anxiety
in patients with or without in vitro fertilization/intracytoplasmic sperm injection treatment.
However, the lack of high-quality studies makes it challenging to make a solid and precise
conclusion. Well-designed studies should be undertaken in the future to confirm these results |