چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Background: Occult spinal dysraphism (OSD) represents a spectrum of congenital anomalies that are characterized by skincovered lesions without exposed neural tissue, which can cause rostrocaudal traction on the spinal cord. Prophylactic surgery has a high likelihood of changing the natural history in which a gradual loss of function may be replaced by clinical stability. Detection of OSD in infants is difficult because an abnormal neurological examination is often not apparent until the child becomes ambulatory, or even later. Cutaneous signs are often the initial markers of congenital spine abnormalities and investigation of skin lesions in these patients may lead to earlier diagnosis of OSD. This study was conducted to investigate the frequency and type of cutaneous stigmata in different forms of OSD. Methods: In a prospective study, 39 patients with OSD were referred to our hospital from August 23, 2001 to March 20, 2010. Results: A total of 39 patients, 15 (38.5%) males and 24 (61.5%) females, with the age range of 4 months to 41 years (mean= 12.8 y) were included in this study. Skin stigmata were present in 66.66% of patients and most frequent findings were hypertrichosis followed by lipoma. Conclusions: The discovery of a midline skin lesion in an otherwise well, asymptomatic neonate or child often prompts a search for OSD using imaging modalities. Cutaneous markers in a high percentage accompany spinal malformations. They can aid the clinician in further diagnostic and therapeutic work. The knowledge of these skin lesions can guide the clinician to underlying spinal pathology. Key Words: spinal dysraphisms, occult spinal dysraphism, skin lesions (Neurosurg Q 2014;24:63–66) Raphe is a line in which fusion between symmetrical embryonic structures occurs in midline. Lack of the mentioned fusion would lead to dysraphism.1 Spinal dysraphism is a term referring to all kinds of developing disorders in back midline, from the outer skin to the vertebrae and the spinal cord.2 Spinal dysraphism consists of a spectrum of congenital anomalies that occur due to the incomplete closure of neural tube in early stages of embryo formation.3,4 Spinal dysraphisms are divided into 2 groups of open or uncovered and occult; this classification is based on the presence or absence of normal skin over lesions. Occult spinal dysraphism (OSD) defects include a spectrum of congenital anomalies causing clinical symptoms and spinal cord injury by rostrocaudal traction on the spinal cord. These patients tend to have dermatologic and orthopedic disorders.2 OSD is difficult to be diagnosed in infants, because in most cases it is asymptomatic at birth5 and neurological symptoms are not often diagnosable until the child starts walking.4 Cutaneous marks are often the initial sign of congenital spinal disorders.6 Consequently, paying attention to skin lesions is crucial for diagnosis and early treatment of OSD and can prevent complications in these patients. |
| نویسنده | نفر چندم مقاله |
|---|---|
| ایرج لطفی نیا | اول |
| صمد اسلام جمال گلزاری | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| CR-Dysraphism.pdf | 1398/08/20 | 253420 | دانلود |
