چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Nanozymes are nanoparticulated structures with the inherent enzymatic activities, which their advances inbio/nanomedicine field are progressively growing regarding their exceptional properties, such as nano-size, irregular shape, rich surface chemistry, low cost production, etc. These features enable nanos-tructures to mimic the cellular antioxidant enzymes as novel candidates for treatment of oxidative stress-induced disorders. Oxidative stress reflect sprincipally an imbalance between generation of reac-tive oxygen species(ROS), such as hydroxyl and superoxide radicals, and the level of antioxidant defense system, so that this imbalance can lead to harsh pathological conditions. Here we present prevalent nanozyme antioxidants as well as their therapeutic concerns from diverse points of view including bio/cytocompatibility and cellular uptake, biomolecular corona, effect of pH and temperatureonenzy-maticfunction, and invivo analysis, which are of paramount importance for reducing the bench-to-clinicgap. |
| نویسنده | نفر چندم مقاله |
|---|---|
| سارا سلاطین | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 1-s2.0-S1748013219303342-main.pdf | 1398/09/16 | 2031398 | دانلود |
