چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Infection with Helicobacter pyloriis very common worldwide. Several non-invasive diagnostic tools are available, mostly limited by use of medications by patients. This study aimed to evaluate efficacy of avidity index for diagnosing the infection during medical treatment.The study sample included patients referred to a gastroenterologist in university clinicof Tabriz University of medical sciences without alarm signs. Sensitivity, specificity and the best cut-off value, positive and negative predictive values for this cut-off are reported for IgG avidity compared to results of stool antigen test. From the total of 200 patients, fifty fulfilled the criteria (mean age was 31.12(7.7) years and 62% were females). Serology was positive in 45 (90.0%) patients. Area under the curve was reported to be 0.753, with standard error=0.078 and 95% confidence interval from 0.600 to 0.907 (p=0.006). The best cut-off for IgG avidity was 82.50. At this level the sensitivity was 0.80 and specificity was 0.74. The positive predictive value for this value will be 75.5% and the negative predictive value will be 78.7%. This pilot study evaluated diagnostic efficacy of H. pyloriIgG avidity compared to results of stool Ag testing and found a good sensitivity and specificity. Clinicians could validate result of a negative stool Ag in more than 70% of patients who can‟t stop using PPIs or antibiotics. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مسعود شیرمحمدی | دوم |
| محمدرضا بنیادی | سوم |
| مرتضی قوجازاده | چهارم |
| محمد حسین صومی | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Value of IgG avidity.pdf | 1398/07/25 | 283670 | دانلود |
