| Among the various nano/biomaterials used in cancer treatment, the beauty and
benefits of DNA nanocomposites are outstanding. The specificity and programmability of the
base pairing of DNA strands, together with their ability to conjugate with different types of
functionalities have realized unsurpassed potential for the production of two- and threedimensional nano-sized structures in any shape, size, surface chemistry and functionality.
This review aims to provide an insight into the diversity of static DNA nanodevices,
including DNA origami, DNA polyhedra, DNA origami arrays and bioreactors, DNA
nanoswitch, DNA nanoflower, hydrogel and dendrimer as young but promising platforms
for cancer theranostics. The utility and potential of the individual formats in biomedical
science and especially in cancer therapy will be discussed. |