| The aim of this study was to document some epidemiological features of termination of pregnancy for birth defects in Iran. Westudied 603 pregnant women who were diagnosed/recommended for the termination of pregnancy as having a fetus with sometypes of birth defect(s). Most women (87.2 percent) had at least one ultrasound examination. The proportion of other screeningtests including amniocentesis and genetic tests were 2.8 and 4.6 percent, respectively. Of 603 women, 201 terminated the pregnancygiving a prevalence rate of 33.3 percent (CI 95%: 29.6–37.6). The remaining 402 subjects were unable to get the permission forabortion because of untimely diagnosis/application for termination (20th week of pregnancy and/or later). Forty-eight percentof termination of pregnancies was performed before the 18th week of pregnancy. Neural tube defects, limb deformation, hydropsfetalis, hydrocephaly, and chromosomal anomalies including Down syndrome accounted proportionally for about 65 percent ofdefects eligible for abortion in the region. Although the rate of termination of pregnancy for birth defects is acceptable at thecurrent situation in the country, more efforts should still be made to convince the community authorities to give more possibilityand ease for the termination of pregnancy for congenital anomalies |