Effect of L. acidophilus and B. lactis on blood glucose in women with gestational diabetes mellitus a randomized placebo‑controlled trial

Effect of L. acidophilus and B. lactis on blood glucose in women with gestational diabetes mellitus a randomized placebo‑controlled trial


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نویسندگان: عزیز همایونی راد , فرناز صحاف ابراهیمی , متانت مسن , فاطمه عباسعلیزاده , لیلا خلیلی

کلمات کلیدی: Gestational diabetes mellitus, Probiotic, Yoghurt

نشریه: 9311 , 75 , 11 , 2019

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نویسنده ثبت کننده مقاله عزیز همایونی راد
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده تغذیه
کد مقاله 69322
عنوان فارسی مقاله Effect of L. acidophilus and B. lactis on blood glucose in women with gestational diabetes mellitus a randomized placebo‑controlled trial
عنوان لاتین مقاله Effect of L. acidophilus and B. lactis on blood glucose in women with gestational diabetes mellitus a randomized placebo‑controlled trial
ناشر 6
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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AbstractBackground:Gestational diabetes mellitus (GDM) is a complication of pregnancy that can be associated with neona-tal complications and adverse pregnancy outcomes. Recently, probiotic use has been proposed for better control of glucose in GDM patients. The aim of this study was to evaluate the effect of probiotic yoghurt compare with ordinary yoghurt on GDM women.Methods:In this double-blind placebo-controlled clinical trial, 84 pregnant women with GDM were randomly assigned into two groups of 42 recipients who underwent 300 g/day of probiotic yoghurt or placebo for 8 weeks. Blood glucose, HbA1c, and the outcome of pregnancy were compared between the two groups after the intervention.Results:According to the findings of present trial no significant differences were observed in general characteristics between the two groups (p > 0.05). Both fasting and post prandial blood glucose as well as the level of HbA1c were decreased significantly in probiotic group (p < 0.05), although these changes are not statistically significant in the pla-cebo group. The between group differences was significant after the 2 month intervention (p < 0.05). Neonates born of probiotic group mothers, have significantly lower weight and fewer macrosome neonates were born in this group compared with control group (p < 0.05). However, no difference was observed in other values of outcome.Conclusions:Our study revealed that better control of blood glucose can be achieved by consumption of probiotic yoghurt in patients whose pregnancy is complicated by GDM, compared with placebo. Also incidence of macrosomia may be decreased by this regimen.

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نویسنده نفر چندم مقاله
عزیز همایونی راددوم
فرناز صحاف ابراهیمیاول
متانت مسنسوم
فاطمه عباسعلیزادهچهارم
لیلا خلیلیششم

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