Identification and applications of neuroactive silk proteins: a narrative review
Identification and applications of neuroactive silk proteins: a narrative review
نویسندگان: احد بناگذار محمدی , سعید صدیق اعتقاد , محمدعلی تربتی , سید محمد باقر فضل جو , سید مهدی وطن دوست , صمد اسلام جمال گلزاری , فرشته فرج دخت , جواد محمودی
کلمات کلیدی: Fibroin; Neuroprotection; Sericin; Silk proteins
نشریه: 16961 , 3 , 17 , 2019
| نویسنده ثبت کننده مقاله |
جواد محمودی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات علوم اعصاب |
| کد مقاله |
69290 |
| عنوان فارسی مقاله |
Identification and applications of neuroactive silk proteins: a narrative review |
| عنوان لاتین مقاله |
Identification and applications of neuroactive silk proteins: a narrative review |
| ناشر |
8 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Abstract
In traditional medicine, natural silk is regarded as a cognitive enhancer and a cure for ameliorating the symptoms of heart disease,
atherosclerosis, and metabolic disorders. In this review, general characteristics of both silk proteins, fibroin and sericin, extracted
from silkworm Bombyx mori and their potential use in the neuronal disorders was discussed. Evidence shows that silk proteins exhibit
neuroprotective effects in models of neurotoxicity. The antioxidant, neuroprotective, and acetylcholinesterase inhibitory mechanisms
of silk proteins could prove promising in the treatment of neurodegenerative diseases. Owing to their excellent neurocompatibility and
physicochemical properties, silk proteins have been used as scaffolds and drug delivery materials in the neuronal tissue engineering.
These data support the potential of silk proteins as an effective complementary agent for central and peripheral neurological disorders. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| R-Silk.pdf | 1398/07/20 | 626771 | دانلود |