| خلاصه مقاله | Background: Aphasia is an acquired language injury as the result of the stroke in the left hemisphere that may result in the loss of cerebral function. However, the brain can use neuroplasticity to adjust itself functionally, by reorganizing the cortical maps, which contributes to the stroke recovery. The current study aimed at reviewing the literature on the effects of neuroplasticity and factors affecting language recovery of patients with aphasia Methods: An electronic search was performed in PMC, Web of Science, PubMed, Scopus, Medline, SID, Google Scholar, and Ovid databases. The present information is available reviewing the articles from 1996 to 2019 through the search of the resources. Results: Neuroplasticity is the capacity of a brain to change or be modified at cellular or behavioral levels. The changes in the cortex organization include an increase in the number and density of dendrites, synapse, and neurotrophic factors synthesis and establishing of new neuronal circuits. Recent advances in functional imaging reveal that cortical hemisphere contralateral to the infarction lesion plays an important role in this recovery process. There is also clinical evidence showing that the contralesional intact hemisphere plays an important role in compensation for impaired functions. This brain plasticity can lead to the degree of spontaneous recovery, and rehabilitative training may modify and boost the neuronal plasticity processes. Conclusion: The central nervous system is plastic, in that the number and strength of synaptic connections change over time. The growing understanding of the nature of brain plasticity raises optimism that this knowledge can be capitalized upon to improve rehabilitation efforts and to optimize functional outcome. The therapists focus on maximizing the functional benefits of poststroke motor rehabilitation by developing interventions to promote motor learning-related neuroplasticity. |