چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| طاهر انتظاری ملکی | دوم |
| ناصر اصلان آبادی | سوم |
| فریبا پورکریم | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Angioplasty, Contrast-induced nephropathy (CIN), Pentoxifylline, Diabetes |
| خلاصه مقاله | Introduction and background: Contrast-induced nephropathy (CIN) is one of the complications of contrast media usage for diagnosis or treatment of heart diseases. We aimed to evaluate the efficacy of pentoxifylline (PTX) for the prevention of CIN in patients with diabetes undergoing angioplasty. In this study, cystatin C has been used as a novel marker of renal function. Methods: The present study was a randomized clinical trial study. This investigation focuses on 90 diabetic patients over 18 years old who had been referred to Shahid Maddani Hospital for angioplasty. Patients were assigned randomly into two groups. For cases group besides routine procedures, 400 mg PTX three times per day from 24 hours before to 24 hours after angioplasty was administered orally. The control group only received routine procedures. In order to evaluate renal function, cystatin C levels in patients 24 h after angioplasty measured and compared. Results: The initial value of cystatin C were measured (Case group=0.39±1.31 and control group=0.42±1.24), after angioplasty the value for both groups increased (Case group=0.61±1.33 and control group=0.47±1.31). This increase was not significant in any of the groups (respectively, P=0.673 and P=0.244). Comparison of cystatin C value after angioplasty in both groups did not show a statistically significant difference (P=0.912). Discussion and Conclusion: The results of this investigation have indicated that the use of PTX had no significant effect on prevention of CIN in diabetic patients after angioplasty. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Evaluation of preventive effects of pantoxifylline.pdf | 1398/06/28 | 519615 | دانلود |
| certificate.Evaluation of preventive effects of pantoxifylline.pdf | 1398/06/28 | 533740 | دانلود |
