چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| ساناز حامدیزدان | اول |
| فاطمه فتحی آزاد | دوم |
| فرزانه لطفی پور بناب | چهارم |
| پریناز پورعبداله کلیبر | پنجم |
| مینا مطلب زاده خانمیری | ششم |
| امیرمحمد گلوانی | سوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Lamiaceae; Marrubium crassidens, Minimal inhibitory, Concentrations |
| خلاصه مقاله | Marrubium crassidens endemic to Armenia, Azarbaijan, Turkey and Iran is used in folk medicine for a variety of ailments. The goal of our study was to assess the biological activity of M. crassidens testing the methanol extract of aerial parts of the plant for its antimicrobial activity against 5 known bacteria and a fungus. The air-dried aerial parts of M. crassidens were successively extracted with petroleum ether (40–60°C), dichloromethane and methanol via maceration at room temperature. The agar disc diffusion method was employed to determine the microbial growth inhibitory properties of the methanol extract against both Gram-positive and Gram-negative bacteria species; Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Pseudomonas aeruginosa, Escherichia coli, and a fungus; Candida albicans. Besides, minimal inhibitory concentrations (MICs) were also determined by agar serial dilution method for the strains of bacteria which had zone of microbial growth inhibition to evaluate the inhibitory properties. The methanol extract of M. crassidens revealed moderated activity when evaluated against pathogenic microorganisms of S. aureus and S. epidermidis (Gram positive bacteria) with inhibition zone of 11.2 ± 0.4 and 10.5 ± 0.8 mm, and MIC of 1 and 0.5 mg/μl, respectively. Overall, M. crassidens methanol extract showed antibacterial activity against two gram positive microorganisms whereas differences in microbial susceptibility were registered. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 2019-09-05 10.17.25.jpg | 1398/06/14 | 1072763 | دانلود |
| 2.xps | 1398/06/14 | 271760 | دانلود |
