چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| A brief review on various solubilisation techniques of coxibs is provided and the solubility of celecoxib (CXB) in binary solvent mixtures of {carbitol (1) + water (2)} is reported at temperatures ranging from 298.2 to 313.2 K. Three cosolvency models, i.e. Yalkowsky model, Jouyban–Acree model and the Jouyban–Acree–van’t Ho ff model, have been used for correlating the reported data, and the mean relative deviations are employed to evaluate the accuracy of the fi tness. Solubilities are also predicted by the generally trained version of the Jouyban–Acree model and its combined model with Abraham solute parameters previously proposed for {carbitol (1) + water (2)} binary mixtures. Furthermore, the apparent thermodynamic properties of dissolution process of CXB in all -investigated solvents were calculated according to van’t Ho ff and Gibbs equations. |
| نویسنده | نفر چندم مقاله |
|---|---|
| فاطمه نوروزی | اول |
| ابوالقاسم جویبان | دوم |
| محمد برزگر جلالی | چهارم |
| الهه رحیم پور | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Solubility of celecoxib in carbitol + water mixtures.pdf | 1398/05/22 | 1672101 | دانلود |
