Human umbilical cord mesenchymal stem cells derived-exosomes in diseases treatment
Human umbilical cord mesenchymal stem cells derived-exosomes in diseases treatment
نویسندگان: یودا یعقوبی , علی اکبر موثق پور اکبری , مجید زمانی , مهدی طالبی , امیر مهدی زاده حقیقی , مهدی یوسفی
کلمات کلیدی: Exosome
Human umbilical cord
Mesenchymal stem cells
Clinical application
نشریه: 22959 , 2019 , 233 , 2019
| نویسنده ثبت کننده مقاله |
مهدی یوسفی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز سلولهای بنیادی |
| کد مقاله |
68391 |
| عنوان فارسی مقاله |
Human umbilical cord mesenchymal stem cells derived-exosomes in diseases treatment |
| عنوان لاتین مقاله |
Human umbilical cord mesenchymal stem cells derived-exosomes in diseases treatment |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Exosomes are extracellular vesicles with the size of 40–100 nm in diameter and a density of 1.13–1.19 g/mL,
containing proteins, mRNAs, miRNAs, and DNAs. Exosomes change the recipient cells biochemical features
through biomolecules delivery and play a role in cellular communication. These vesicles are produced from body
fluids and different cell types like mesenchymal stem cells (MSCs). Evidence suggests that mesenchymal stem
cells-derived exosome (MSC-EXO) exhibit functions similar to MSCs with low immunogenicity and no tumorization.
MSCs can also be isolated from a variety of sources including human umbilical cord (HUC). Because of
the non-invasive collection method, higher proliferation and lower immunogenicity, HUCMSC-EXO has been
frequently used in regenerative medicine and various diseases treatment compared to the other MSC-EXO resources.
This review aimed to investigate the applications of HUCMSC-EXO in different diseases. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 9bb6fd5e5fdc9e0fcebe87bda15e311f.pdf | 1398/05/18 | 4107437 | دانلود |