چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Abstract Marrubium genus belongs to Lamiaceae family, which is one of the precious genera native to Iran, while the phytochemical studies upon Marrubium spp. are limited. Regarding the various usages of Marrubium spp. in traditional medicine, extensive studies have been carried out in the field of pharmacological studies, in which there various effects such as antimicrobial, anti-inflammatory, anti-spasmodic, hypoglycemic and lipid-lowering effects, and etc. from these species have been revealed. The aerial parts of four Marrubium spp. (M. crassidens, M. persicum, M. propinquum, and M. parviflorum) were collected uring their flowering stages from Varzeghan and Marand provinces from Azarbaijan, Iran in 1395. Dried plant materials were solvent extracted separately with petroleum ether, chloroform and methanol via maceration method. Afterwards, the antioxidant activities of the extracts were evaluated through scavenging the free DPPH radicals. Besides, the total phenolic and flavonoid contents of the extracts were verified based on colorimetric relative techniques. The antioxidant evaluation established the lowest RC50 of 11.1μg/mL for the 40% Sep-Pak fraction of the M. crassidens methanol extract. Moreover, petroleum ether extracts revealed no antioxidant activity. The most total phenolics and flavonoids content were reported in . crassidens methanol extract with 512.6 mg gallic acid equivalent and 212.7 mg quercetin equivalent both in 100 g dried plant material. The presence of phenoli and flavonoids contents had good antioxidant potential in these Marrubium spp. Overall, M. crassidens possessed higher phenolic and flavonoid contents resulting in superior antioxidant activity compared to other three species. |
| نویسنده | نفر چندم مقاله |
|---|---|
| ساناز حامدیزدان | سوم |
| نگار ناصری | اول |
| فاطمه فتحی آزاد | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| eco.pdf | 1398/05/14 | 338540 | دانلود |
